Classification and therapy of germ cell tumors in anterior mediastinum

Primary mediastinal tumors. Part 1: tumors of the anterior mediastinum.

Primary anterior mediastinal neoplasms comprise a diverse group of tumors and account for 50% of all mediastinal masses. Thymomas are most common and can be locally invasive and associated with parathymic syndromes. Thymic carcinomas and thymic carcinoids are rare malignancies with a propensity for local invasion and distant metastases. Thymolipomas are benign thymic tumors. The mediastinal ger...

genetics of testicular germ cell tumors

testicular germ cell tumor (tgct) is the most solid tumor in 20-40 years old man. tgct account for 95% of testicular tumors and represent a unique type of human cancer from several different perspectives. tgct arise by transformation of germ cells. the transformed germ cells exhibit ploripotentially to differentiate into embryonic. extra-embryonic, and somatic tissue types, and are highly sensi...

Classification of Testicular Germ Cell Tumors: Insights from Immunohistochemistry

Testicular tumors are rare. It was estimated that there would be approximately 8,000 new cases reported in the United States in 2007 and only 380 cancer-related deaths. Germ cell tumors (GCT) comprise about 98% of all testicular tumors and for most of the deaths. They are the most common malignancy and one of the most common causes of cancer-related death in males between the ages of 15 and 35 ...

Survival of Children with Germ Cell Tumors in Ali Asghar Hospital since 1990 to 2003

Background and Objective: Germ cell tumor (GCT) accounts for approximately 2-3% of all malignancies in children. In this respect, about 20% of patients with GCT are still resistant to therapy. Materials and Methods: The cross-sectional strategy of this survey was undertaken on 57 patients with germ cell ...

Claudins and Germ Cell Tumors